Innovative non-animal human-based tools and strategies for biomedical research
Closed
Status as published by the data source.
Expected Outcome:
This topic aims at supporting activities that are enabling or contributing to one or several expected impacts of destination 5 “Unlocking the full potential of new tools, technologies and digital solutions for a healthy society”. To that end, proposals under this topic should aim for delivering results that are directed towards and contributing to several of the following Expected Outcomes:
• Researchers utilise tools and strategies that are more relevant to the human situation as compared to the currently used animal models.
• Fewer live animals are used in biomedical research.
• Health technology developers will get access to improved human-relevant tools or strategies allowing for a faster pace of innovation.
• Legislators and regulators will benefit from strengthened EU leadership in non-animal based biomedical research that is socially accepted and sustainable.
• Healthcare providers and patients will benefit from innovative tools or strategies opening up novel biomedical concepts enabling improved disease prediction, prevention and treatment. Scope:
The proposal(s) should develop and/or use tools and strategies that address critical areas of biomedical research where animal-models are currently used but are of limited translational value for investigation and development of prevention and treatment. Such advanced tools and strategies should aim at a better understanding of the pathogenesis of disorders that feature a high impact on public health and exhibit a high rate of animal use or severe animal suffering, and enable to develop biomedical concepts with increased translational value, thereby ultimately leading to improved disease prediction, prevention and treatment.
The proposals should address all of the following aspects:
• The innovative tools and strategies should include a variety of technologies and methodological approaches such as –omics and other high-throughput procedures, human-derived cell-based material, organoids, micro-physiological systems, and in-silico models.
• The newly proposed tools and strategies should demonstrably advance the state-of-the-art in specific areas of biomedical research.
• Prospects and avenues for dissemination, knowledge sharing, uptake or translation into health policies of the proposed tools and strategies within the EU should be provided.
• Aspects such as harm and cost-benefit assessment as well as ease of production with respect to current practices should also be considered.
• Criteria for model qualification and standardisation should be developed in well-justified use-case contexts to demonstrate their translational values. Proposals could consider the involvement of the European Commission's Joint Research Centre (JRC) to provide added-value regarding such aspects as supporting validation of emerging approaches, promotion of research results, and the interfacing with the regulatory community. In this respect, the JRC is open to collaborate with any successful proposal after the selection process has been completed.
All projects funded under this topic are strongly encouraged to participate in networking and joint activities. These networking and joint activities could, for example, involve the participation in joint workshops, the exchange of knowledge, the development and adoption of best practices, or joint communication activities. Therefore, proposals are expected to include a budget for the attendance to regular joint meetings and may consider covering the costs of any other potential joint activities without the prerequisite to detail concrete joint activities at this stage. The details of these joint activities will be defined during the grant agreement preparation phase. In this regard, the Commission may take on the role of facilitator for networking and exchanges, including with relevant stakeholders.
This topic requires the effective contribution of social sciences and humanities (SSH) disciplines and the involvement of SSH experts, institutions as well as the inclusion of relevant SSH expertise, in order to produce meaningful and significant effects enhancing the societal impact of the related research activities.
Applicants invited to the second stage and envisaging to include clinical studies should provide details of their clinical studies in the dedicated annex using the template provided in the submission system. See definition of clinical studies in the introduction to this work programme part.
- Status
- Closed
- Deadline
- (time not stated)
- Opens
- Published
- Total budget
- €25,000,000
- Grant range
- €4,000,000 – €8,000,000
- Country
- European Union (EU-wide)
- Programme
- Horizon Europe (HORIZON)
- Official page
- Open at the source portal
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Where this came from
- Source document
- https://ec.europa.eu/info/funding-tenders/opportunities/data/topicDetails/horizon-hlth-2024-tool-05-06-two-stage.json
- Document fingerprint
c7913e9aed1f4757(SHA-256, first 16 hex characters)- Retrieved
- First recorded here
What has changed
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- currency first recorded as EUR on
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- budget_total first recorded as 25000000.00 on
- deadline first recorded as 2024-04-11 on
- opens_on first recorded as 2023-03-30 on
- published_on first recorded as 2022-12-07 on
- status_basis first recorded as source_status on
- status first recorded as closed on
- title first recorded as Innovative non-animal human-based tools and strategies for biomedical research on
Data source
© European Union, 2026. Source: EU Funding & Tenders Portal. Reused under Commission Decision 2011/833/EU — CC BY 4.0.
Retrieved from the source on .
The source last updated this document on Mon, 13 Apr 2026 11:42:42 GMT.
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